MAPKBP1 antibody
ORB154035
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAPKBP1
Overview
- SupplierBiorbyt
- Product NameMAPKBP1 antibody
- Delivery Days Customer16
- ApplicationsWestern Blot, ELISA
- Applications SupplierWB: 1:200-500, IHC-P: 1:50-100 ELISA, WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23005
- Target nameMAPKBP1
- Target descriptionmitogen-activated protein kinase binding protein 1
- Target synonymsJNK-binding protein 1; JNKBP1; JNKBP-1; mitogen-activated protein kinase-binding protein 1; NPHP20
- HostRabbit
- IsotypeIgG
- Protein IDO60336
- Protein NameMitogen-activated protein kinase-binding protein 1
- Scientific DescriptionRabbit polyclonal antibody to MAPKBP1. MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP1 (mitogenactivated protein kinase binding protein 1), also known as JNKBP1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptorassociated factor 2) and Tak1 (TGF beta activated kinase 1), MAPKBP1 is thought to act an adaptor protein for NFkB (nuclear factor kB) activation. MAPKBP1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, PraderWilli syndrome, TaySachs disease and Marfan syndrome are all associated with defects in chromosome 15localized genes.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203