Western blot All lanes: MARK1 antibody IgG at 2.65ug/ml + Rat heart tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 90, 73, 85 kDa Observed band size: 90 kDa

MARK1 Antibody

CSB-PA873719DSR1HU

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Rat

TargetMARK1

Overview

Supplier
Cusabio
Product Name
MARK1 Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID4139
Target name
MARK1
Target description
microtubule affinity regulating kinase 1
Target synonyms
MARK, Par-1c, Par1c, serine/threonine-protein kinase MARK1, MAP/microtubule affinity-regulating kinase 1, PAR1 homolog c
Host
Rabbit
Isotype
IgG
Protein IDQ9P0L2
Protein Name
Serine/threonine-protein kinase MARK1
Scientific Description
Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Reactivity
Human, Rat
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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MARK1 Antibody

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