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MART-1 / Melan-A / MLANA (Melanoma Marker) (MLANA/1761R), CF405S conjugate, 0.1mg/mL [26628-22-8]

MART-1 / Melan-A / MLANA (Melanoma Marker) (MLANA/1761R), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC041761
Biotium
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rabbit, Rat
TargetMLANA
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Overview

  • Supplier
    Biotium
  • Product Name
    MART-1 / Melan-A / MLANA (Melanoma Marker) (MLANA/1761R), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MLANA/1761R
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID2315
  • Target name
    MLANA
  • Target description
    melan-A
  • Target synonyms
    antigen LB39-AA; antigen SK29-AA; epididymis secretory sperm binding protein; MART1; MART-1; melanoma antigen recognized by T-cells 1; protein Melan-A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ16655
  • Protein Name
    Melanoma antigen recognized by T-cells 1
  • Scientific Description
    This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse, Rabbit, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203