MART-1-Specific TCR Lentivirus (Clone DMF4)
78678
Product group Molecular Biology
Overview
- SupplierBPS Bioscience
- Product NameMART-1-Specific TCR Lentivirus (Clone DMF4)
- Delivery Days Customer7
- CertificationResearch Use Only
- Scientific DescriptionThe human MART-1-specific T Cell Receptor lentiviruses (clone DMF4) are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce a human TCR (clone DMF4) that specifically recognizes antigen MART-1 (Melanoma-associated antigen recognized by T cells-1, or Melan-A), and in which the TCR alpha chain and beta chain are linked by P2A (Figure 1). The lentiviruses also transduce a puromycin selection gene. Figure 1. (A) Schematic of the lenti-vector used to generate the MART-1-specific TCR lentivirus and (B) Construct diagram showing expressed components of the MART-1-specific TCR. TRAV and TRAC correspond to the TCR alpha chain variable and constant regions, respectively, whereas TRBV and TRBC correspond to the TCR beta chain variable and constant regions.
- Storage Instruction-80°C
- UNSPSC12352200