Masitinib (mesylate) (Standard) [1048007-93-7]

MedChem Express

Masitinib (mesylate) (Standard) [1048007-93-7]

5

1048007-93-7

CHEMICAL,detergents_surfactants

Research Use Only

594.75

Masitinib (mesylate) (Standard) is the analytical standard of Masitinib (mesylate). This product is intended for research and analytical applications. Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRalpha/beta (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity[1][2][4].

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