Masitinib (Standard)

MedChem Express

Masitinib (Standard) [790299-79-5]

5

Research Use Only

Masitinib (Standard) is the analytical standard of Masitinib. This product is intended for research and analytical applications. Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit ( IC 50 =200 nM for human recombinant c-Kit). It also inhibits PDGFRalpha/beta ( IC 50 s=540/800 nM), Lyn ( IC 50 = 510 nM for LynB), Lck , and, to a lesser extent, FGFR3 and FAK . Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity [1] [2] [4] .

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