Masticadienonic acid

MedChem Express

Masticadienonic acid [514-49-8]

999

Research Use Only

C30H46O3

454.68

Masticadienonic acid is an orally active and selective inhibitor of MAPK (p38, ERK, JNK) and NF-kappaB pathways and an agonist of the Nrf2 pathway. Masticadienonic acid reduces the release of pro-inflammatory cytokines such as TNFalpha, IL-1beta, and IL-6, restores the expression of intestinal tight junction proteins (ZO-1, occludin), and modulates gut microbiota. Masticadienonic acid is promising for research of inflammatory bowel disease[1].

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12352200