MAT-POS-e194df51-1

MedChem Express

MAT-POS-e194df51-1

14

Research Use Only

98.45

C24H21ClN4O3S

480.97

MAT-POS-e194df51-1 is an orally active, non-covalent and non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 value of 37nM. MAT-POS-e194df51-1 is cytotoxic with EC50 values of 64 nM and 126 nM in A549-ACE2-TMPRSS2 cells and HeLa -ACE2 cells, respectively[1].

N#CC1(CC1)CS(=O)(N2CC3=C([C@@H](C2)C(NC4=C5C=CC=CC5=CN=C4)=O)C=C(C=C3)Cl)=O

-20°C,2°C to 8°C

12352200