Mavacamten (MYK-461)

AbMole BioScience

Mavacamten (MYK-461)

9

1642288-47-8

Chemical

Research Use Only

C15H19N3O2

273.33

Mavacamten, also known as SAR-439152 and MYK-461, is the first (first-class) orally bioavailable allosteric and reversible selective inhibitor of Cardiac Myosin. The IC50 of bovine heart and human heart was 490 nM and 711 nM, respectively.

CC(C)N1C(=O)NC(=CC1=O)NC(C)C2=CC=CC=C2

-20°C, sealed

12352200