Mavatrep(JNJ-39439335)

Biorbyt

Mavatrep(JNJ-39439335) [956274-94-5]

10

956274-94-5

Research Use Only

C25N2OF3H21

422.4423

Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 microM) of CYP isoforms 3A4, 1A2, and 2D6.

OC(C)(C)C1=CC=CC=C1C2=CC=C3N=C(/C=C/C4=CC=C(C(F)(F)F)C=C4)NC3=C2

12352200