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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA883444LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA883444LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA883444LA01HU at dilution of 1:100

MBD1 Antibody

CSB-PA883444LA01HU
Cusabio
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMBD1
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Overview

  • Supplier
    Cusabio
  • Product Name
    MBD1 Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4152
  • Target name
    MBD1
  • Target description
    methyl-CpG binding domain protein 1
  • Target synonyms
    CXXC3, PCM1, RFT, methyl-CpG-binding domain protein 1, CXXC-type zinc finger protein 3, protein containing MBD 1, protein containing methyl-CpG-binding domain 1, the regulator of fibroblast growth factor 2 (FGF-2) transcription
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UIS9
  • Protein Name
    Methyl-CpG-binding domain protein 1
  • Scientific Description
    Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1. Probably forms a complex with SETDB1 and ATF7IP that represses transcription and couples DNA methylation and histone Lys-9 trimethylation. Isoform 1 and isoform 2 can also repress transcription from unmethylated promoters.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

FAQ

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