MC-?Ala-?Ala-?Asn(Trt)?-?PAB

Biorbyt

MC-?Ala-?Ala-?Asn(Trt)?-?PAB

10

Research Use Only

C46H50N6O8

814.94

MC-?Ala-?Ala-?Asn(Trt)?-?PAB, is a hetero bifunctional cross-linker, useful in antibody drug conjugation (ADC). MC-?Ala-?Ala-?Asn(Trt)?-?PAB is a fissionable linker which is specifically activated in a tumor microenvironment. XQN70430 was reported in patent WO 2016026458.

O=C(C[C@H](NC([C@@H](NC([C@@H](NC(CCCCCCN1C(C=CC1=O)=O)=O)C)=O)C)=O)C(NC2=CC=C(C=C2)O)=O)NC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5

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