MC-betaglucuronide-MMAE-2 [1703778-81-7]

MedChem Express

MC-betaglucuronide-MMAE-2 [1703778-81-7]

10

1703778-81-7

Research Use Only

C63H93N9O20

1296.46

MC-betaglucuronide-MMAE-2 is a agent-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide.

O[C@H]1[C@H](O)[C@@H](O)[C@H](OC2=C(NC(CCNC([C@H](CN)N3C(C=CC3=O)=O)=O)=O)C=C(COC(N(C)[C@@H](C(C)C)C(N[C@H](C(N(C)[C@@H]([C@H](CC)C)[C@H](OC)CC(N4[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C5=CC=CC=C5)=O)CCC4)=O)=O)C(C)C)=O)=O)C=C2)O[C@@H]1C(O)=O

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