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ProductsBack/MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan [2414254-52-5]

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan [2414254-52-5]

HY-148668A
MedChem Express
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Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan [2414254-52-5]
  • Delivery Days Customer
    10
  • CAS Number
    2414254-52-5
  • Certification
    Research Use Only
  • Estimated Purity
    95.11
  • Molecular Formula
    C55H60FN9O13
  • Molecular Weight
    1074.12
  • Scientific Description
    MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 microM)[1].
  • SMILES
    O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C3CC3)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    41115800