MC-Val-Cit-PAB

Biorbyt

MC-Val-Cit-PAB [159857-80-4]

16

159857-80-4

Research Use Only

C28N6O7H40

572.6532

MC-Val-Cit-PAB, also known as MC-Val-Cit-PAB-OH, is a cathepsin cleavable ADC peptide linker. MC-Val-Cit-PAB is useful for making ADC conjugate (antibody-drug conjugate). FDA approved drugs such as brentuximab vedotin used this linker.

O=C([C@]([H])(C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(C([H])=C([H])C1=O)=O)=O)N([H])[C@]([H])(C(N([H])C1C([H])=C([H])C(C([H])([H])O[H])=C([H])C=1[H])=O)C([H])([H])C([H])([H])C([H])([H])N([H])

12352200