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ProductsBack/Mc-Val-Cit-PAB-Cl [1639351-92-0]

Mc-Val-Cit-PAB-Cl [1639351-92-0]

HY-112099
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Mc-Val-Cit-PAB-Cl [1639351-92-0]
  • Delivery Days Customer
    9
  • CAS Number
    1639351-92-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.67
  • Molecular Formula
    C28H39ClN6O6
  • Molecular Weight
    591.10
  • Scientific Description
    Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
  • SMILES
    O=C(N1CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(CCl)C=C2)=O)=O)=O)C=CC1=O
  • Storage Instruction
    -20°C
  • UNSPSC
    41115800

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