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MCC950 [210826-40-7]

MCC950 [210826-40-7]

T3701
TargetMol Chemicals
CAS Number210826-40-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.30%
Molecular Weight404.48
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    MCC950 [210826-40-7]
  • Delivery Days Customer
    16
  • CAS Number
    210826-40-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    MCC950
  • Estimated Purity
    98.30%
  • Molecular Formula
    C20H24N2O5S
  • Molecular Weight
    404.48
  • Scientific Description
    CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1beta secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically inhibited activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes. MCC950 reduced IL-1beta production in vivo and attenuated the severity of experimental autoimmune encephalomyelitis (EAE), a disease model of multiple sclerosis.
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)(O)c1coc(c1)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200