Mcl-1 inhibitor 10

MedChem Express

Mcl-1 inhibitor 10 [1580484-33-8]

5

Research Use Only

C21H15F3O4

388.34

Mcl-1 inhibitor 10 (compound 43) is a relatively strong MCL-1 inhibitor (IC50=0.67 microM). Mcl-1 inhibitor 10 interacts with specific binding sites of MCL-1 protein to block the pro-survival signal of MCL-1 and push cancer cells into apoptosis. Mcl-1 inhibitor 10 can be used in the study of MCL-1 dependent cancers[1].

O=C(C1=CC(C2=C(COC3=CC=CC(C(F)(F)F)=C3)C=CC=C2)=CC=C1O)O

12131703