MCL1 antibody
GTX102026
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetMCL1
Overview
- SupplierGeneTex
- Product NameMCL1 antibody
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.33 mg/ml
- ConjugateUnconjugated
- Gene ID4170
- Target nameMCL1
- Target descriptionMCL1 apoptosis regulator, BCL2 family member
- Target synonymsBCL2 family apoptosis regulator; BCL2L3; bcl2-L-3; bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; induced myeloid leukemia cell differentiation protein Mcl-1; Mcl-1; MCL1, BCL2 family apoptosis regulator; mcl1/EAT; MCL1-ES; MCL1L; MCL1S; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1 (BCL2-related); TM
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Activation of Aldehyde Dehydrogenase 2 Ameliorates Glucolipotoxicity of Pancreatic Beta Cells. Chen SM et al., 2021 Oct 6, BiomoleculesRead more
- The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells. Takino JI et al., 2019 Nov 13, Sci RepRead more
- Response of Myeloid Leukemia Cells to Luteolin is Modulated by Differentially Expressed Pituitary Tumor-Transforming Gene 1 (PTTG1) Oncoprotein. Chen PY et al., 2018 Apr 12, Int J Mol SciRead more
- Methamphetamine Induces Apoptosis of Microglia via the Intrinsic Mitochondrial-Dependent Pathway. Sharikova AV et al., 2018 Sep, J Neuroimmune PharmacolRead more
- Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ. Lee WY et al., 2017 Nov 1, Int J CancerRead more
- The CHAC1-inhibited Notch3 pathway is involved in temozolomide-induced glioma cytotoxicity. Chen PH et al., 2017 Apr, NeuropharmacologyRead more
- Return to quiescence of mouse neural stem cells by degradation of a proactivation protein. Urban N et al., 2016 Jul 15, ScienceRead more
- MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. Peng HY et al., 2016, PLoS OneRead more
- Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1. Lee WY et al., 2015 Sep 29, OncotargetRead more
- Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells. Lin MH et al., 2014 Jul 25, Chem Biol InteractRead more