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ProductsBack/Mcl1-IN-11 [2042211-13-0]
CgoaEWY7MCqEFSZCAAAAAA-8OxI757.png
CgoaEWY7MCqEFSZCAAAAAA-8OxI757.png
CgoaEWY7MCqEFSZCAAAAAA-8OxI757.png

Mcl1-IN-11 [2042211-13-0]

Research Use Only
T11973
TargetMol Chemicals
CAS Number2042211-13-0
DownloadMSDS
Product group Chemicals
Molecular Weight683.88
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Mcl1-IN-11 [2042211-13-0]
  • Delivery Days Customer
    72
  • CAS Number
    2042211-13-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Mcl1-IN-11
  • Molecular Formula
    C38H41N3O5S2
  • Molecular Weight
    683.88
  • Scientific Description
    Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor with Kis of 0.06 microM and 4.2 microM for Mcl-1 and Bcl-2, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    CC1(C)C=2C(=CC(C)=C(C(=C)C3=CC=C(C(NS(=O)(=O)C4=CC(N(=O)=O)=C(NCCSC5=CC=CC=C5)C=C4)=O)C=C3)C2)C(C)(C)CC1
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.
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