Mcl1-IN-15 [518303-27-0]
HY-W286906
CAS Number518303-27-0
Product group Chemicals
Molecular Weight445.55
Overview
- SupplierMedChem Express
- Product NameMcl1-IN-15 [518303-27-0]
- Delivery Days Customer5
- CAS Number518303-27-0
- CertificationResearch Use Only
- Molecular FormulaC22H23NO5S2
- Molecular Weight445.55
- Scientific DescriptionMcl1-IN-15 (Compound 7) is the inhibitor for myeloid cell leukemia 1 (Mcl-1) with an IC50 of 8.73 microM. Mcl1-IN-15 inhibits Mcl1-BH3 peptide interaction, activates the Bak/Bax-mediated apoptosis and exhibits antitumor activity[1].
- SMILESO=C(O)CSC1=CC(NS(=O)(C2=CC=C(C(C)(C)C)C=C2)=O)=C3C=CC=CC3=C1O
- UNSPSC12352200