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MCM2 antibody [N1N2], N-term

Research Use Only
GTX103071
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetMCM2
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    MCM2 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Antibody Specificity
    IP/MS validation was supported by references (PMID:30377385)
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4171
  • Target name
    MCM2
  • Target description
    minichromosome maintenance complex component 2
  • Target synonyms
    BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance protein 2 homolog; MITOTIN; nuclear protein BM28
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat Methods
    Read more
  • MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach. Cheung CHY et al., 2017 Oct 16, Sci Rep
    Read more