McN-A-343

MedChem Express

McN-A-343 [55-45-8]

10

55-45-8

Research Use Only

99.77

C14H18Cl2N2O2

317.21

McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis [1] [2] . McN-A-343 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(NC1=CC(Cl)=CC=C1)OCC#CC[N+](C)(C)C.[Cl-]

-20°C,2°C to 8°C

12352200