MCP-1/CCL2, Cynomolgus (HEK293, His)
HY-P700787
Protein IDP61274
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameMCP-1/CCL2, Cynomolgus (HEK293, His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Gene ID102135739
- Target nameCCL2
- Target descriptionC-C motif chemokine ligand 2
- Target synonymsMCP-1, MCP1, SCYA2, C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, Small-inducible cytokine A2, monocyte chemoattractant protein-1
- Protein IDP61274
- Protein NameC-C motif chemokine 2
- Scientific DescriptionMCP-1/CCL2 protein activates CCR2 and induces chemotaxis and calcium ion mobilization. It attracts monocytes and basophils, not neutrophils or eosinophils. It also contributes to neuropathic pain and enhances synaptic transmission in dopamine neurons. MCP-1/CCL2 exists as a monomer or homodimer and binds to endothelial cells through proteoglycans. It interacts with TNFAIP6 via its Link domain. MCP-1/CCL2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MCP-1/CCL2 protein, expressed by HEK293 , with C-His labeled tag.
- UNSPSC41116100
