Bio-Connect

MCP-1/CCL2, Cynomolgus (HEK293, His)

HY-P700787
MedChem Express
Protein IDP61274
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MCP-1/CCL2, Cynomolgus (HEK293, His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Gene ID102135739
  • Target name
    CCL2
  • Target description
    C-C motif chemokine ligand 2
  • Target synonyms
    MCP-1, MCP1, SCYA2, C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, Small-inducible cytokine A2, monocyte chemoattractant protein-1
  • Protein IDP61274
  • Protein Name
    C-C motif chemokine 2
  • Scientific Description
    MCP-1/CCL2 protein activates CCR2 and induces chemotaxis and calcium ion mobilization. It attracts monocytes and basophils, not neutrophils or eosinophils. It also contributes to neuropathic pain and enhances synaptic transmission in dopamine neurons. MCP-1/CCL2 exists as a monomer or homodimer and binds to endothelial cells through proteoglycans. It interacts with TNFAIP6 via its Link domain. MCP-1/CCL2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MCP-1/CCL2 protein, expressed by HEK293 , with C-His labeled tag.
  • UNSPSC
    41116100