MCT1-IN-3 [2878360-80-4]

TargetMol Chemicals

MCT1-IN-3 [2878360-80-4]

4

Chemical

Research Use Only

MCT1-IN-3

98.87%

C22H19N3O4

389.4

MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor, targeting solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) for cancer treatment. MCT1-IN-3 (compound 24) showed the highest MCT1 transport inhibition with an IC50 value of 81.0 Nm and also exhibits significant inhibitory activity against the multidrug transporter ABCB1.

3 years

C(=C(C(OC)=O)C#N)C=1C=2C(N(CC(NC3=CC=C(OC)C=C3)=O)C1)=CC=CC2

-20°C

51202000