IHC-P analysis of human spleen tissue using GTX85065 MD1 antibody. Working concentration : 2.5 microg/ml
MD1 antibody
GTX85065
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLY86
Overview
- SupplierGeneTex
- Product NameMD1 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9450
- Target nameLY86
- Target descriptionlymphocyte antigen 86
- Target synonymsdJ80N2.1; ly-86; lymphocyte antigen 86; MD1; MD-1; MD-1, RP105-associated; MMD-1; protein MD-1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionToll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203