MD2-TLR4-IN-1

AbMole BioScience

MD2-TLR4-IN-1

9

2249801-12-3

Chemical

Research Use Only

C22H14Cl2N4O

421.28

MD2-TLR4-IN-1 is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-alfa) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 uM and 0.53 uM, respectively.

ClC1=C(C(=CC=C1)Cl)C(=O)NC2=CC3=C([NH]N=C3C4=CC5=C([NH]C=C5)C=C4)C=C2

12352200