IHC-P analysis of human brain tissue using GTX55364 MDC1 (phospho Ser513) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
IHC-P analysis of human brain tissue using GTX55364 MDC1 (phospho Ser513) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
MDC1 (phospho Ser513) antibody
GTX55364
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMDC1
Overview
- SupplierGeneTex
- Product NameMDC1 (phospho Ser513) antibody
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9656
- Target nameMDC1
- Target descriptionmediator of DNA damage checkpoint 1
- Target synonymshomologue to Drosophila photoreceptor protein calphotin; mediator of DNA damage checkpoint protein 1; NFBD1; nuclear factor with BRCT domains 1
- HostRabbit
- IsotypeIgG
- Protein IDQ14676
- Protein NameMediator of DNA damage checkpoint protein 1
- Scientific DescriptionThe protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203