MeBIO
M21232
CAS Number667463-95-8
Product group Chemicals
Molecular Weight370.20
Overview
- SupplierAbMole BioScience
- Product NameMeBIO
- Delivery Days Customer9
- CAS Number667463-95-8
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC17H12BrN3O2
- Molecular Weight370.20
- Scientific DescriptionMeBIO, an analog of 6-bromoindirubin-3'-oxime, has been suggested to possess the structural basis for a potent and selective inhibitor of glycogen synthase kinase-3 (GSK3) and cyclin-dependent kinases. MeBIO displays minimal activity against CDK1/Cyclin B, GSK-3, and CDK5/p25 (IC50 values are 92.0, 44-100 and >100 uM respectively). MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist.
- UNSPSC12352200