Mebiol Gel

Cosmo Bio USA

Mebiol Gel

16

Research Use Only

Note: This product is packaged with RP Drying Agent packs to absorb moisture, oxygen and corrosive gases. It is therefore subject to European Commerce Area Import Regulation (EC) No. 1272/2008 - Classification, Labeling, and Packaging of Substances and Mixtures (CLP). Applies to EEA (i.e. EU27 countries, Iceland, Liechtenstein, Norway, UK). For additional information, see the following: OSHA Europe RP Agent Manufactuers Statement Introduction to Mebiol® Gel Hydrogels are a diverse class of polymeric materials characterized by their network-like structure and high water content. Hydrogels of many kinds have found a wide variety of applications in medicine and life science research weighted towards, but not at all limited to three-dimensional cell culture, tissue engineering, and drug delivery. Properties highly favorable to cell culture and tissue engineering applications prompted the commercialization of Mebiol® Gel, a copolymer of poly(N-isopropylacrylamide) and poly(ethylene glycol) (PNIPAAm-PEG) for research purposes in the early 2000s. Mebiol® Gels defining feature, in contrast to other commercially available hydrogels, is its temperature reversible sol-gel transition. When cooled, Mebiol® Gel is a sol (handles like a liquid) but becomes a rigid hydrogel at higher temperatures. In practice, this means extremely easy cell handling. Cultures are seeded into cooled Mebiol® Gel and recovered conveniently by cooling the culture vessel and centrifugation. In the gel state, the highly lipophylic environment of the Mebiol® Gel presents an efficient niche for cell proliferation, cell communication, gas and mass exchange, and protection of cells and tissue from shear forces. <input alt= src=https://www.cosmobiousa.com/content/images/cosmo-bio-ltd/mbg-pmw20-1001_mebiol-gel_14841.jpg type=image> Features Easy handling Non-toxic, biocompatible 100% synthetic, pathogen free High transparency for cell observation Proven performance. Preparation <input alt= src=https://www.cosmobiousa.com/content/images/cosmo-bio-ltd/mbg-pmw20-1001_mebiol-gel_14847.jpg type=image> Application Stem cell and pluripotent stem cell culture, expansion, and differentiation Spheroid culture Cell implantation Organ and Tissue Regeneration Drug Delivery Non-cell culture application Application Examples Technical Notes References and Literature Frequently Asked Questions Dynamic Viscoelastic Property of Mebiol® Gel Temperature dependence of the dynamic moduli of the aqueous solution of Mebiol® Gel at a concentration of 10 wt% in distilled water. Storage modulus (G, solid lines) and loss modulus (G, broken lines) were measured on heating (closed symbols) and cooling (open symbols) at the oscillatory frequency of 1 Hz.

41105300