MED27 antibody

GeneTex

MED27 antibody

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.82 mg/ml

Unconjugated

MED27

mediator complex subunit 27

cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa; CRAP34; CRSP complex subunit 8; CRSP34; CRSP8; epididymis secretory sperm binding protein; MED3; mediator of RNA polymerase II transcription subunit 27; NEDSCAC; p37 TRAP/SMCC/PC2 subunit; transcriptional coactivator CRSP34; TRAP37

Rabbit

IgG

Mediator of RNA polymerase II transcription subunit 27

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203