Medetomidine [86347-14-0]

TargetMol Chemicals

Medetomidine [86347-14-0]

14

86347-14-0

Chemical

Research Use Only

Medetomidine

C13H16N2

200.28

Medetomidine (Domtor) is a potent, highly selective alpha2-adrenoceptor agonist, demonstrating Ki values of 1.08 nM for alpha2-adrenoceptors and 1750 nM for alpha1-adrenoceptors, indicating significant selectivity for alpha2 over alpha1 receptors compared to clonidine and UK 14,304 with 1620-, 220-, and 300-fold respectively. Medetomidine significantly inhibits the twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0), showcasing its efficacy. Exhibiting a wide range of pharmacological effects, Medetomidine is effective in vivo, manifesting hypotensive, bradycardic, sedative, anxiolytic, hypothermic, and analgesic properties.

3 years

C(C)(C1=C(C)C(C)=CC=C1)C2=CN=CN2

-20°C

12352200