Medetomidine HCl [86347-15-1]

Chemodex

Medetomidine HCl [86347-15-1]

10

86347-15-1

Research Use Only

>98%

Warning

C13H17ClN2

236.75

Chemical. CAS: 86347-15-1. Formula: C13H17ClN2. MW: 236.75. Synthetic. Medetomidine is an imidazole derivative. It acts as a potent selective agonist of alpha2-adrenoceptors (Ki=1.08nM vs. 1750nM for alpha1-adrenoceptors). Through its effect on alpha2-adrenoceptors, medetomidine has sedative, antinociceptive, hypotenisve, bradycardic, anxiolytic, analgesic and hypothermic actions. Its effects on pain are additive or synergistic with fentanyl-type opioids. The effects of medetomidine are effectively countered by alpha2-adrenoceptor antagonists, like atipamezole. Selective alpha2-adrenoceptor agonists, including medetomidine, have anesthetic sparing properties, greatly reducing the dose of anesthetic required following premedication with the alpha2-adrenoceptor agonist. - Medetomidine is an imidazole derivative. It acts as a potent selective agonist of alpha2-adrenoceptors (Ki=1.08nM vs. 1750nM for alpha1-adrenoceptors). Through its effect on alpha2-adrenoceptors, medetomidine has sedative, antinociceptive, hypotenisve, bradycardic, anxiolytic, analgesic and hypothermic actions. Its effects on pain are additive or synergistic with fentanyl-type opioids. The effects of medetomidine are effectively countered by alpha2-adrenoceptor antagonists, like atipamezole. Selective alpha2-adrenoceptor agonists, including medetomidine, have anesthetic sparing properties, greatly reducing the dose of anesthetic required following premedication with the alpha2-adrenoceptor agonist.

CC1=CC=CC(C(C)C2=CNC=N2)=C1C.Cl

-20°C,2°C to 8°C

12352200