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Chemical Structure
Chemical Structure
Chemical Structure

Meglumine [6284-40-8]

Research Use Only
AG-CN2-0413
AdipoGen Life Sciences
CAS Number6284-40-8
Product group Chemicals
Estimated Purity>95% (NMR)
Molecular Weight195.2
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Meglumine [6284-40-8]
  • Delivery Days Customer
    10
  • CAS Number
    6284-40-8
  • Certification
    Research Use Only
  • Estimated Purity
    >95% (NMR)
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C7H17NO5
  • Molecular Weight
    195.2
  • Scientific Description
    Chemical. CAS: 6284-40-8. Formula: C7H17NO5. MW: 195.2. Synthetic. Amino sugar derived from sorbitol. Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell membranes with comparable osmotic activity like sodium. Widely used in the preparation of contrast/radiopaque media in combination with iodine containing compounds, such as diatrizoate meglumine and iodipamide meglumine. Examples of meglumine-combined drugs are flunixin meglumine (used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis). - Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell membranes with comparable osmotic activity like sodium. Widely used in the preparation of contrast/radiopaque media in combination with iodine containing compounds, such as diatrizoate meglumine and iodipamide meglumine. Examples of meglumine-combined drugs are flunixin meglumine (used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis).
  • SMILES
    [H]C(O)(CO)C([H])(O)C([H])(O)C([H])(O)CNC
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200

References

  • Ternary amorphous composites of celecoxib, poly(vinyl pyrrolidone) and meglumine with enhanced solubility: P. Gupta & A.K. Bansal; Pharmazie 60, 830 (2005)
  • Modeling of drug release from celecoxib-PVPmeglumine amorphous system: P. Gupta & A.K. Bansal; PDA. J. Pharm. Sci. Technol. 59, 346 (2005)
  • Molecular interactions in celecoxib-PVPmeglumine amorphous system: P. Gupta & A.K. Bansal; J. Pharm. Pharmacol. 57, 303 (2005)
  • Enhanced oral delivery of antimony from meglumine antimoniate/b-cyclodextrin nanoassemblies: F. Frezard, et al.; Int. J. Pharm. 347, 102 (2008)
  • Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine: M. Fujita, et al.; Chem. Pharm. Bull. 57, 1096 (2009)
  • Stabilization by meglumine of an amine compound degraded by formaldehyde in tablets: M. Fujita, et al.; Int. J. Pharm. 386, 195 (2010)