Chemical Structure
Meglumine [6284-40-8]
AG-CN2-0413
Overview
- SupplierAdipoGen Life Sciences
- Product NameMeglumine
- Delivery Days Customer10
- CAS Number6284-40-8
- CertificationResearch Use Only
- Estimated Purity>95%
- Molecular FormulaC7H17NO5
- Molecular Weight195.2
- Scientific DescriptionChemical. CAS: 6284-40-8. Formula: C7H17NO5. MW: 195.2. Synthetic. Amino sugar derived from sorbitol. Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell membranes with comparable osmotic activity like sodium. Widely used in the preparation of contrast/radiopaque media in combination with iodine containing compounds, such as diatrizoate meglumine and iodipamide meglumine. Examples of meglumine-combined drugs are flunixin meglumine (used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis). - Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell membranes with comparable osmotic activity like sodium. Widely used in the preparation of contrast/radiopaque media in combination with iodine containing compounds, such as diatrizoate meglumine and iodipamide meglumine. Examples of meglumine-combined drugs are flunixin meglumine (used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis).
- SMILES[H]C(O)(CO)C([H])(O)C([H])(O)C([H])(O)CNC
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
References
- Ternary amorphous composites of celecoxib, poly(vinyl pyrrolidone) and meglumine with enhanced solubility: P. Gupta & A.K. Bansal; Pharmazie 60, 830 (2005)
- Modeling of drug release from celecoxib-PVPmeglumine amorphous system: P. Gupta & A.K. Bansal; PDA. J. Pharm. Sci. Technol. 59, 346 (2005)
- Molecular interactions in celecoxib-PVPmeglumine amorphous system: P. Gupta & A.K. Bansal; J. Pharm. Pharmacol. 57, 303 (2005)
- Enhanced oral delivery of antimony from meglumine antimoniate/b-cyclodextrin nanoassemblies: F. Frezard, et al.; Int. J. Pharm. 347, 102 (2008)
- Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine: M. Fujita, et al.; Chem. Pharm. Bull. 57, 1096 (2009)
- Stabilization by meglumine of an amine compound degraded by formaldehyde in tablets: M. Fujita, et al.; Int. J. Pharm. 386, 195 (2010)