mEH-IN-1 [2418576-06-2]

MedChem Express

mEH-IN-1 [2418576-06-2]

5

2418576-06-2

Research Use Only

98.0

C16H17F6NOS

385.37

mEH-IN-1 (Compound 62) is a potent microsomal epoxide hydrolase (mEH) inhibitor with the IC50 of 2.2 nM. The mEH is a mammalian alpha/beta-fold hydrolase enzyme, expressed in almost all tissues, hydrolyzes a wide range of epoxide containing molecules. The mEH is mainly localized in the endoplasmic reticulum (ER) of eukaryotic cells. mEH-IN-1 can be used for the research of preeclampsia, hypercholanemia and cancer[1].

NC(C(C1CCCC1)SCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O

-20°C

12131703