WB analysis of various samples using GTX66729 MEK2 (phospho Thr394) antibody. Lane1 : HEK293T whole cell lysate(40ug) Lane2 : HEK293T treated with UV for 5 minutes then repair for 16 hours whole cell lysate(40ug) Lane3 : The Kidney tissue lysate of Rat(40ug) Lane4 : The Kidney tissue lysate of Mouse(40ug) Dilution : 1:2000
WB analysis of various samples using GTX66729 MEK2 (phospho Thr394) antibody. Lane1 : HEK293T whole cell lysate(40ug) Lane2 : HEK293T treated with UV for 5 minutes then repair for 16 hours whole cell lysate(40ug) Lane3 : The Kidney tissue lysate of Rat(40ug) Lane4 : The Kidney tissue lysate of Mouse(40ug) Dilution : 1:2000
MEK2 (phospho Thr394) antibody
GTX66729
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAP2K2
Overview
- SupplierGeneTex
- Product NameMEK2 (phospho Thr394) antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5605
- Target nameMAP2K2
- Target descriptionmitogen-activated protein kinase kinase 2
- Target synonymsCFC4; dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; MAP kinase kinase 2; MAPK/ERK kinase 2; MAPKK2; MEK2; mitogen-activated protein kinase kinase 2, p45; MKK2; PRKMK2
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203