MEK/PI3K-IN-1 [2281803-28-7]
HY-144692
CAS Number2281803-28-7
Product group Chemicals
Molecular Weight913.63
Overview
- SupplierMedChem Express
- Product NameMEK/PI3K-IN-1 [2281803-28-7]
- Delivery Days Customer10
- CAS Number2281803-28-7
- CertificationResearch Use Only
- Molecular FormulaC36H37F5IN9O6
- Molecular Weight913.63
- Scientific DescriptionMEK/PI3K-IN-1 (compound 6r) is a potent MEK/PI3K inhibitor, with IC50 values of 124 nM (MEK1), 130 nM (PI3Kalpha), and 236 nM (PI3Kdelta), respectively. MEK/PI3K-IN-1 suppresses pAKT and pERK1/2 levels. MEK/PI3K-IN-1 shows anti-proliferative activity against tumor cell lines[1].
- SMILESO=C(C1=C(C(F)=C(C=C1)F)NC2=CC=C(C=C2F)I)NOCCOCCOCCOCCNC3=NC(N4CCOCC4)=NC(N5C(C(F)F)=NC6=C5C=CC=C6)=N3
- UNSPSC12352200