MEK/PI3K-IN-2 [2281803-33-4]
HY-144693
CAS Number2281803-33-4
Product group Chemicals
Molecular Weight957.68
Overview
- SupplierMedChem Express
- Product NameMEK/PI3K-IN-2 [2281803-33-4]
- Delivery Days Customer10
- CAS Number2281803-33-4
- CertificationResearch Use Only
- Molecular FormulaC38H41F5IN9O7
- Molecular Weight957.68
- Scientific DescriptionMEK/PI3K-IN-2 (compound 6s) is a potent MEK/PI3K inhibitor, with IC50 values of 352 nM (MEK1), 107 nM (PI3Kalpha), and 137 nM (PI3Kdelta), respectively. MEK/PI3K-IN-2 suppresses pAKT and pERK1/2 levels. MEK/PI3K-IN-2 shows anti-proliferative activity against tumor cell lines[1].
- SMILESO=C(C1=C(C(F)=C(C=C1)F)NC2=CC=C(C=C2F)I)NOCCOCCOCCOCCN(C3=NC(N4CCOCC4)=NC(N5C(C(F)F)=NC6=C5C=CC=C6)=N3)CCO
- UNSPSC12352200