MEL23
HY-148106
Molecular Weight354.40
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameMEL23 [642072-49-9]
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC19H22N4O3
- Molecular Weight354.40
- Scientific DescriptionMEL23 is a MDM2 E3 ligase inhibitor that blocks the E3 ligase activity of the MDM2-MDMX complex. MEL23 inhibits Mdm2 and p53 ubiquitination in cells, reduce viability of cells with wild-type p53. MEL23 stabilizes MDM2 via a mechanism independent of p53 transcription[1].
- SMILESO=C1NC(C(C2NCCC3=C2NC4=C3C=CC=C4)C(N1CCCC)=O)=O
- UNSPSC12131703