Melanoma associated antigen antibody [HMB45]
GTX71957
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameMelanoma associated antigen antibody [HMB45]
- Delivery Days Customer9
- Application Supplier NoteFor IF: Use at an assay dependent dilution. For IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHMB45
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis antibody reacts with an antigen present in cutaneous melanocytes, prenatal and infantile retinal pigment epithelium and melanoma cells.This antibody reacts with melanomas and tumors showing melanoma/melanocytic differentiation. It reacts with junctional and blue nevus cells. Non-melanocytic cells do not react with this antibody.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Loss of GPNMB Causes Autosomal-Recessive Amyloidosis Cutis Dyschromica in Humans. Yang CF et al., 2018 Feb 1, Am J Hum GenetRead more
- Interferon-inducible T-cell alpha chemoattractant (ITAC) induces the melanocytic migration and hypopigmentation through destabilizing p53 via histone deacetylase 5: a possible role of ITAC in pigment-related disorders. Lee E et al., 2017 Jan, Br J DermatolRead more
- Hyperosmotic stress reduces melanin production by altering melanosome formation. Bin BH et al., 2014, PLoS OneRead more