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Melanoma Marker (MART-1 + Tyrosinase + gp100)(DT101+ BC199 + T311 + HMB45), Biotin conjugate, 0.1mg/mL [26628-22-8]

BNCB0704
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetMLANA
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Overview

  • Supplier
    Biotium
  • Product Name
    Melanoma Marker (MART-1 + Tyrosinase + gp100)(DT101+ BC199 + T311 + HMB45), Biotin conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    DT101 BC199 T311 HMB45
  • Concentration
    0.1 mg/ml
  • Conjugate
    Biotin
  • Gene ID2315
  • Target name
    MLANA
  • Target description
    melan-A
  • Target synonyms
    antigen LB39-AA; antigen SK29-AA; epididymis secretory sperm binding protein; MART1; MART-1; melanoma antigen recognized by T-cells 1; protein Melan-A
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203