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MELK, Human (His)

HY-P701811
MedChem Express
Protein IDQ14680
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MELK, Human (His)
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    93.00
  • Gene ID9833
  • Target name
    MELK
  • Target description
    maternal embryonic leucine zipper kinase
  • Target synonyms
    HPK38; maternal embryonic leucine zipper kinase; pEg3 kinase; protein kinase Eg3; protein kinase PK38; tyrosine-protein kinase MELK
  • Protein IDQ14680
  • Protein Name
    Maternal embryonic leucine zipper kinase
  • Scientific Description
    MELK is a multifunctional serine/threonine protein kinase that regulates the cell cycle, stem cell self-renewal, apoptosis, and splicing. MELK phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622, activates apoptosis through MAP3K5/ASK1, helps CDC25B localize during mitosis, and inhibits BCL2L14, which may affect breast cancer occurrence. MELK Protein, Human (His) is the recombinant human-derived MELK protein, expressed by E. coli , with N-6*His labeled tag.
  • Storage Instruction
    -80°C
  • UNSPSC
    41116100

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