MELK, Human (His)
HY-P701811
Protein IDQ14680
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameMELK, Human (His)
- Delivery Days Customer5
- CertificationResearch Use Only
- Estimated Purity93.00
- Gene ID9833
- Target nameMELK
- Target descriptionmaternal embryonic leucine zipper kinase
- Target synonymsHPK38; maternal embryonic leucine zipper kinase; pEg3 kinase; protein kinase Eg3; protein kinase PK38; tyrosine-protein kinase MELK
- Protein IDQ14680
- Protein NameMaternal embryonic leucine zipper kinase
- Scientific DescriptionMELK is a multifunctional serine/threonine protein kinase that regulates the cell cycle, stem cell self-renewal, apoptosis, and splicing. MELK phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622, activates apoptosis through MAP3K5/ASK1, helps CDC25B localize during mitosis, and inhibits BCL2L14, which may affect breast cancer occurrence. MELK Protein, Human (His) is the recombinant human-derived MELK protein, expressed by E. coli , with N-6*His labeled tag.
- Storage Instruction-80°C
- UNSPSC41116100