
Western Blot Positive WB detected in: PC-3 whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate All lanes: MEN1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 69, 68, 64 kDa Observed band size: 75 kDa
MEN1 Recombinant Monoclonal Antibody
CSB-RA242999A0HU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetMEN1
Overview
- SupplierCusabio
- Product NameMEN1 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID8G11
- ConjugateUnconjugated
- Gene ID4221
- Target nameMEN1
- Target descriptionmenin 1
- Target synonymsMEAI; menin; SCG2
- IsotypeIgG
- Protein IDO00255
- Protein NameMenin
- Scientific DescriptionEssential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates Lys-4 of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203