Menin-MLL inhibitor MI-2 [1271738-62-5]
HY-15222
CAS Number1271738-62-5
Product group Chemicals
Estimated Purity99.81
Molecular Weight375.55
Overview
- SupplierMedChem Express
- Product NameMenin-MLL inhibitor MI-2 [1271738-62-5]
- Delivery Days Customer5
- CAS Number1271738-62-5
- CertificationResearch Use Only
- Estimated Purity99.81
- Molecular FormulaC18H25N5S2
- Molecular Weight375.55
- Scientific DescriptionMenin-MLL inhibitor MI-2 is a competitive and selective Menin-MLL interaction inhibitor with an IC50 value of 446 nM and a Ki value of 158 nM. Menin-MLL inhibitor MI-2 downregulates the expression of target genes such as HOXA9 and MEIS1, inhibits proliferation of leukemia cells and induces apoptosis and differentiation. Menin-MLL inhibitor MI-2 is proming for rasearch of MLL-rearranged acute leukemias (e.g., AML, ALL)[1].
- SMILESCCCC1=CC2=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C2S1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![Menin-MLL inhibitor MI-2 [1271738-62-5]](https://www.targetmol.com/group3/M00/35/78/CgoaEGayICyEVt8VAAAAAE6i9EU379.png)