![MeOSuc-AAPV-pNA [70967-90-7] MeOSuc-AAPV-pNA [70967-90-7]](https://www.targetmol.com/group3/M00/35/43/CgoaEWayGo-EN2ugAAAAAJkWezU436.png)
MeOSuc-AAPV-pNA [70967-90-7]
T38363
Overview
- SupplierTargetMol Chemicals
- Product NameMeOSuc-AAPV-pNA [70967-90-7]
- Delivery Days Customer16
- CAS Number70967-90-7
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameMeOSuc-AAPV-pNA
- Molecular FormulaC27H38N6O9
- Molecular Weight590.63
- Scientific DescriptionProteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.
- Shelf life instruction3 years
- SMILESCOC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)Nc1ccc(cc1)[N+]([O-])=O
- Storage Instruction-20°C
- UNSPSC12352200