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MeOSuc-AAPV-pNA [70967-90-7]

MeOSuc-AAPV-pNA [70967-90-7]

T38363
TargetMol Chemicals
CAS Number70967-90-7
Product group Chemicals
Molecular Weight590.63
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    MeOSuc-AAPV-pNA [70967-90-7]
  • Delivery Days Customer
    16
  • CAS Number
    70967-90-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    MeOSuc-AAPV-pNA
  • Molecular Formula
    C27H38N6O9
  • Molecular Weight
    590.63
  • Scientific Description
    Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.
  • Shelf life instruction
    3 years
  • SMILES
    COC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)Nc1ccc(cc1)[N+]([O-])=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200