
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA013695ESR1HU at dilution of 1:100
MEOX1 Antibody
CSB-PA013695ESR1HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetMEOX1
Overview
- SupplierCusabio
- Product NameMEOX1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4222
- Target nameMEOX1
- Target descriptionmesenchyme homeobox 1
- Target synonymshomeobox protein MOX-1; KFS2; MOX1
- HostRabbit
- IsotypeIgG
- Protein IDP50221
- Protein NameHomeobox protein MOX-1
- Scientific DescriptionMesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203