WB analysis of mouse cardiac myocyte lysate using GTX22478 Merlin (phospho Ser518) antibody. Lane 1 : Mock Lane 2 : 4 nM CLA-treated cells Lane 3 : 20 nM CLA-treated cells Lane 4 : 100 nM CLA-treated cells Dilution : 1:1000
WB analysis of mouse cardiac myocyte lysate using GTX22478 Merlin (phospho Ser518) antibody. Lane 1 : Mock Lane 2 : 4 nM CLA-treated cells Lane 3 : 20 nM CLA-treated cells Lane 4 : 100 nM CLA-treated cells Dilution : 1:1000
Merlin (phospho Ser518) antibody
GTX22478
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityMouse
TargetNF2
Overview
- SupplierGeneTex
- Product NameMerlin (phospho Ser518) antibody
- Delivery Days Customer9
- Antibody SpecificityThis phospho-specific polyclonal antibody is specific for phosphorylated pS518 of human NF2 (neurofibromatosis 2 gene product). Reactivity with non-phosphorylated Human NF2 (Merlin) is minimal by ELISA.
- Application Supplier NoteWB: 1:500-1:2000. ELISA: 1:200000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4771
- Target nameNF2
- Target descriptionneurofibromin 2
- Target synonymsACN; BANF; bilateral acoustic neurofibromatosis; merlin; merlin-1; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromin 2 (bilateral acoustic neuroma); SCH; schwannomerlin; schwannomin
- HostRabbit
- IsotypeIgG
- Protein IDP35240
- Protein NameMerlin
- Scientific DescriptionThe recently isolated neurofibromatosis 2 tumor suppressor gene encodes a 595 amino acid protein (Merlin). The protein product Merlin, named for its relatedness to the ezrin, radixin and moesin (ERM) family of proteins, is a tumor suppressor whose absence results in the occurrence of multiple tumors of the nervous system, particularly schwannomas and meningiomas. Merlins similarity to ERMs suggests that it might share functions, acting as a link between cytoskeletal components and the cell membrane. The NF2 protein is highly expressed in human fibroblasts and detected as a single band of about 75kD. This antibody is specific for the phosphorylated form of human NF2 (Merlin).
- ReactivityMouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203