Merlin (phospho Ser518) antibody

GeneTex

Merlin (phospho Ser518) antibody

9

WB: 1:500-1:2000. ELISA: 1:200000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

NF2

neurofibromin 2

ACN; BANF; bilateral acoustic neurofibromatosis; merlin; merlin-1; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromin 2 (bilateral acoustic neuroma); SCH; schwannomerlin; schwannomin

Rabbit

IgG

Merlin

The recently isolated neurofibromatosis 2 tumor suppressor gene encodes a 595 amino acid protein (Merlin). The protein product Merlin, named for its relatedness to the ezrin, radixin and moesin (ERM) family of proteins, is a tumor suppressor whose absence results in the occurrence of multiple tumors of the nervous system, particularly schwannomas and meningiomas. Merlins similarity to ERMs suggests that it might share functions, acting as a link between cytoskeletal components and the cell membrane. The NF2 protein is highly expressed in human fibroblasts and detected as a single band of about 75kD. This antibody is specific for the phosphorylated form of human NF2 (Merlin).

-20°C or -80°C,2°C to 8°C

12352203