Mesoridazine

MedChem Express

Mesoridazine [5588-33-0]

10

5588-33-0

Research Use Only

95.62

C21H26N2OS2

386.57

Mesoridazine (TPS-23) , a metabolite of Thioridazine (HY-B0965A), acts as an orally active phenothiazine antipsychotic agent . Mesoridazine is a potent and rapid open-channel blocker of human ether-a-go-go related gene?(hERG) channels and blocks hERG currents with an IC 50 of 550 nM (at 0 mV) in human embryonic kidney 293 cells [1] .Mesoridazine can be used for the research of schizophrenia, as well as certain other psychiatric disorders [1] [2] .

O=S(C(C=C1N2CCC3N(C)CCCC3)=CC=C1SC4=C2C=CC=C4)C

-20°C,2°C to 8°C

12352200