Bio-Connect

Metarrestin [1443414-10-5]

HY-120118
MedChem Express
CAS Number1443414-10-5
Product group Chemicals
Estimated Purity99.90
Molecular Weight474.60
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Metarrestin [1443414-10-5]
  • Delivery Days Customer
    10
  • CAS Number
    1443414-10-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.90
  • Molecular Formula
    C31H30N4O
  • Molecular Weight
    474.60
  • Scientific Description
    Metarrestin (ML246) is an orally active, first-in-class and specific perinucleolar compartment inhibitor. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2. Metarrestin blocks metastatic development and extends survival in mouse cancer models[1][2].
  • SMILES
    O[C@H]1CC[C@H](N(C=NC2=C3C(C4=CC=CC=C4)=C(C5=CC=CC=C5)N2CC6=CC=CC=C6)C3=N)CC1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200